Turning the tables on remodeling

Today’s standard surgical procedure leads to negative remodeling in up to 75% of patients.
In the DARTS Trial, the AMDS resulted in positive remodeling in over 85% of patients and documented effective one-stage malperfusion treatment.

Today’s standard surgical procedure leads to negative remodeling in approximately up to 75% of patients.
In the DARTS Trial, the AMDS resulted in positive remodeling in over 85% of patients and documented effective one-stage malperfusion treatment.

AMDS Clinical Benefits

Positive Aortic Remodeling

The AMDS was specifically designed to induce remodeling and healing of the aortic arch, which is- successfully demonstrated in the DARTS Trial. In addition to this , DARTS also documented positive remodeling of the descending aorta in 85% of patients.

Malperfusion Treatment

DARTS I documented effective one-stage treatment of dynamic malperfusion (cerebral, visceral extremity and spinal cord).

Improved Survival

DARTS I showed improved survival versus standard of care historical controls.
AMDS DARTS Trial
AMDS DARTS Trial

Ascyrus Medical data on file- cohort of patients submitted for CE marking

*Three (10%) patients were admitted with paralysis and all recovered full lower extremity function following AMDS implantation.

Case Examples

Closing the anastomotic entry tear tips the balance to positive remodeling—even in cases where there are additional entry tears.

Publications and Presentations

Journal of Thoracic and Cardiovascular Surgery: Dissected Aorta Repair Through Stent Implantation trial (DARTS): Canadian Experience;

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Journal of Thoracic and Cardiovascular Surgery Editorial Commentary: Did the investigators hit the aortic dissection bullseye with DARTS?

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STS 2019 Presentation

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