Ascyrus Medical Dissection Stent (AMDS)

Cut the complications associated with type A dissection

The AMDS is an arch remodeling graft designed as an adjunct to hemiarch reconstruction. The AMDS reduces the risk of complications from dissection that often require reintervention by stabilizing or reducing the size of the aorta, which is known as positive aortic remodeling.

Up to 75% of patients experience negative aortic remodeling, or aortic diameter growth, after hemiarch reconstruction for a type A dissection, and 40-50% require reintervention for complications including malperfusion and end-organ ischemia.

Add the AMDS to your standard of treatment for acute type A dissections.

type-A-dissections
Close anastomotic tear
Expand and stabilize TL
Arch & arch vessel remodeling and healing
Malperfusion mgmt. and distal remodeling

Seal the anastomotic entry tear

The presence of dissected tissue at the distal anastomosis after standard surgical replacement leaves patients with an anastomotic entry tear that continues to pressurize the false lumen. The AMDS seals the entry tear, stops antegrade pulsatile flow (APF) and decreases pressure in the false lumen.

Cut complexity

The AMDS is designed for rapid deployment during conventional replacement of the ascending aorta and does not require X-ray, hybrid room, or additional vascular access. The system reduces the complexity of type A dissection care without adding significant time to the overall standard procedure.

Induce positive remodeling

Decreasing APF and pressure in the false lumen allows the aortic arch to stabilize or regress in size. This positive remodeling is clinically proven to reduce the complications that over time lead to mortality and invasive secondary procedures.

Treat malperfusion

The AMDS expands, supports, and pressurizes the true lumen to help resolve dynamic malperfusion involving the central and peripheral aortic branches. The AMDS is designed to allow uninhibited blood flow to the arch branches and intercostals to minimize the risk of stroke and paraplegia.

https://www.youtube.com/watch?v=dopSe97AOm0

Device Overview

kink-resistant

Kink resistant and highly adaptable to angulation and diameter changes.

No risk of oversizing due to low radial force that is independent of diameter.

uncovered stent

Uncovered stent allows for uninhibited flow to arch branches and intercostals, minimizing the risk of stroke and paraplegia.

Allows for minimally invasive interventions if needed with up to 12mm stent openings

No risk of migration because the proximal end is sutured in.

Case Benefits

The AMDS system allows for rapid deployment in the aortic arch during the conventional replacement of the ascending aorta and doesn’t add significant time to the overall procedure. No X-ray required. No additional vascular access necessary.

AMDS preserves the native aortic arch and enables minimally invasive management of additional entry tears should it be needed, rather than invasive arch replacement.

Few configurations, combined with a highly adaptable stent, simplifies the case planning process.

By reducing complications and reoperations associated with acute aortic dissections, the AMDS improves the care of patients and may offer significant cost savings for the health care system.

The AMDS system allows for rapid deployment in the aortic arch during the conventional replacement of the ascending aorta and doesn’t add significant time to the overall procedure. No X-ray required. No additional vascular access necessary.

AMDS preserves the native aortic arch and enables minimally invasive management of additional entry tears should it be needed, rather than invasive arch replacement.

Few configurations, combined with a highly adaptable stent, simplifies the case planning process.

By reducing complications and reoperations associated with acute aortic dissections, the AMDS improves the care of patients and may offer significant cost savings for the health care system.

Sizes / Configuration

Straight

AMDS - Straight

Tapered

AMDS - Tapered