The Problem

Today’s standard of treatment for type A dissection isn’t enough.

Aortic dissection is complex and difficult to treat.

Hemiarch replacement alone isn’t enough to stop a type A dissection

from causing significant complications for patients.

Today’s Standard of Care (STD) Aims to:

However, it fails to reliably and confidently address the distal aspects of the disease, resulting in:

The root of the problem is the Distal Anastomotic New Entry Tear (DANE)

Increased utility of high-resolution CT scans has generated new evidence that 50-72% of patients have a DANE detected by CT angiography following acute Debakey I dissection repair.

What happens during an aortic dissection?

The aorta, which is the artery that delivers oxygenated blood from the heart to the body, consists of three layers. A dissection occurs when the inner layer of the aorta tears, and blood is able to flow between the layers.

This creates a false lumen, or an alternate channel where blood is not supposed to flow. When the aorta is split into two layers, the artery is significantly weakened and can rupture if not treated immediately. Over 70% of aortic dissections happen in the ascending aorta just above the heart, classified as Stanford type A.

  • Publication References:
  • Bing F, et al. Vascular and Endovascular Surgery 2014;48(3): 239-245
  • Yasuda S, et al. Circ J doi: 10.1253/circj.CJ-16-0462
  • Tamura K, et al. Eur J Cardio-Thorac Surg 2017;(52): 867–873
  • Rylski B, et al. Eur J Cardio-Thorac Surg 2017:(51):1127-1134
  • Lee TC et al. J Card Surg 2018;33:7-18​
  • Berretta P et al. Ann Cardiothorac Surg 2016(5);4:346-51​
  • Czerny M et al. JACC 2015;65 (24): 2628-35​
  • Nardi P et al. Vessel Plus 2017;1:77-83
  • Halstead JC et al. J Thorac Cardiovasc Surg 2007;133(1):127-135.
  • Concistre G et al. Ann Thorac Surg 2012;93:450-456.
  • Kobuch R et al. J Thorac Cardiovasc Surg 2012;144:300-307.
  • Malvindi PG et al.  Ann Thorac Surg 2013;95:922-928.
  • Olsson C et al. J Vasc Surg 2013;58:333-339.
  • Kimura N et al. J Thorac Cardiovasc Surg 2015;149:S91-98.
  • Roselli EE et al. J Thorac Cardiovasc Surg 2015;149:S117-124.

Cut the complications associated with type A dissection.

Our Solution

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